Listar por autor "Moranta, David"
Mostrando ítems 1-6 de 6
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Apoptosis, toll-like, RIG-I-like and NOD-like receptors are pathways jointly induced by diverse respiratory bacterial and viral pathogens
(Frontiers Media, 2017) Artículo / Artikulua
Lower respiratory tract infections are among the top five leading causes of human death. Fighting these infections is therefore a world health priority. Searching for induced alterations in host gene expression shared by ... -
Deciphering tissue-induced Klebsiella pneumoniae lipid A structure
(National Academy of Sciences, 2015) Artículo / Artikulua
The outcome of an infection depends on host recognition of the pathogen, hence leading to the activation of signaling pathways controlling defense responses. A long-held belief is that the modification of the lipid A ... -
Genome expression profiling-based identification and administration efficacy of host-directed antimicrobial drugs against respiratory infection by nontypeable Haemophilus influenzae
Euba, Begoña; Moleres Apilluelo, Javier
; Segura, Víctor; Viadas Martínez, Cristina ; Morey Sancho, Pau; Moranta, David; Leiva, José; Torres, Juan de; Bengoechea Alonso, José Antonio; Garmendia García, Juncal (American Society for Microbiology, 2015)
Artículo / Artikulua
Therapies that are safe, effective, and not vulnerable to developing resistance are highly desirable to counteract bacterial infections. Host-directed therapeutics is an antimicrobial approach alternative to conventional ... -
Klebsiella pneumoniae outer membrane protein A is required to prevent the activation of airway epithelial cells
(American Society for Biochemistry and Molecular Biology, 2011) Artículo / Artikulua
Outer membrane protein A (OmpA) is a class of proteins highly conserved among the Enterobacteriaceae family and throughout evolution. Klebsiella pneumoniae is a capsulated Gram-negative pathogen. It is an important cause ... -
Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella
(American Society for Microbiology, 2013) Artículo / Artikulua
The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects ... -
Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes
(Public Library of Science, 2013) Artículo / Artikulua
Phagocytosis is a key process of the immune system. The human pathogen Klebsiella pneumoniae is a well known example of a pathogen highly resistant to phagocytosis. A wealth of evidence demonstrates that the capsule ...
